Jeanne Laverne Carmen was born in Paragould, Arkansas. As a child she picked cotton before running away from home at age 13. As a teen, she moved to New York City and landed a job as a dancer in Burlesque, with Bert Lahr. Later she became a model, appearing in several men's magazines. She also became a trick golfer, appearing with Jack Redmond.

In 1998, Carmen was the subject of a TV biography titled "Jeanne Carmen: Queen of the B-Movies", on the series E! True Hollywood Story. The show stated that Carmen maintained a "dangerously close friendship with Marilyn Monroe and The Kennedys" and that after the death of Monroe, Carmen was told to leave town by Chicago mobster Johnny Rosselli who was working for Chicago Mob Boss Sam Giancana. Carmen, believing her life was in danger, fled to Scottsdale, Arizona, where she lived incognito for over a decade. Carmen abandoned her platinum blonde locks, had three children and lived a quiet life, never mentioning her prior life in Hollywood.